Weight loss and gout
Indeed, reducing your weight, particularly quickly, can cause gout to
rear its ugly head. Uric acid is stored in your fatty tissue. It is
soluble in fat and as you loose the fat by burning it off, what is left
is uric acid and it has to go somewhere. As your body tries to deal
with the excess uric acid you are dumping onto it through weight loss,
that uric acid ends up saturating your system and you get a gout
attack.
If you are on allo you have a lot more margin for weight loss because
there is more capacity to remove urate since your body is making a lot
less uric acid and therefore it has more capacity to deal with the
extra uric acid being dumped on your system.
In any event that uric acid is there, in the fat, waiting for you. .
Allopurinol does nothing at all to the uric acid that is already in
your body.