Rheumatology is us
Twinges in joints previously affected by gout..........organic or
super-tentorial?
Given that UA level is around 4.5 dl/mmol monitored.
Muscle spasms.....any grounding/evidence to suggest increased UA implication?
Nature or nurture.......
Don't understand 4.5 dl/mmol, but even at 4.5 mg/dl it may take months,
or even years to get back to what you feel is normal. You are the
gentleman on Pyrazinamide - so again drink mucho, mucho, mucho, in the
sense of mucho, water to avoid kidney stones and damage to
parenchymatous kidney tissue.
Alan
Sulfinpyrazone is a good drug. It is a uricosuric like Probenecid
but acts a lot more quickly - hence the need for plenty of water to
protect the kidneys.
You seem like you have a good handle on all of this. You shouldn't
(although you could) have more breakthrough attacks until the urate
load is low enough.
I would only say (even for the UK) that the UA level should at least
stay below 6.0 mg/dl and probably more like <5 or even lower to
create the negative flow rate to reduce the monosodium urate level to
an acceptable level.
Mr. Bob Bottomley, a knowledgable listmember, had indicated to me
that the accuracy of the personal UA test meter needs to be watched
(probably because of variation of technique by different individuals)-
I interpret his comments to mean "monitor the monitor". He can most
likely address this further for you if you ask him.
I am happy that you have the doc you have, who has found
Sulfinpyrazone (in view of your allergic reaction to Allopurinol) for
you. So now you have many long gout free years ahead of you. Make
sure, though, that once in a while, you have your liver, kidneys and
blood count checked.
Alan