Allopurinol is not for everyone!
Allopurinol is not the total answer for all gout sufferers. I was on Allopurinol for 12 years, it stopped working altogether. My liver became enlarged and the Allopurinol gave me Hepatitis. The doctors told me I was on the brink of liver failure, when I was taken off the drug. The conclusion was that I was on Allopurinol for such a long time (300mg) that I became hypersensitive to the drug.
A 66-year-old female was admitted for rehabilitation of a cerebral hemorrhage on September 11, 1981. Allopurinol, clofibrate, and baclofen were administered. Severe hepatitis developed on November 13. The clinical laboratory data returned to normal on November 30. Challenge tests were conducted on clofibrate, allopurinol, and baclofen. The challenge test was positive after the administration of allopurinol. Allopurinol hepatitis is most likely a hypersensitivity reaction, as is suggested by the symptoms of eosinophilia and rash. Renal dysfunction may predispose one to develop hepatitis associated with allopurinol.
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It is true, there are some who are allergic or hypersensitive to
Allo, but they are relatively few in number.
There are other drugs, PROBENECID, for example, that purge UA from
the system which you may have tolerated better.
What do you do now to control your gout?
I've been on Allo and Probenecid for 40 years although its been a
hit and miss proposition for much of that time. I only really got
with it during the first five to ten years and the last 15 years,
and now I have even added a small daily maintenance dose of
Colchicine.
My last gout attack (and it sent me to the ER) was 14 years ago.
Jack
Consider Probenecid. Before Allo it was all there was aside from
Colchicine.
It doesn't work like Allo, but rather, it purges Uric Acid by
interfering with its reuptake; hence its referred to as a uricosuric.
"Consider Probenecid. Before Allo it was all there was aside from
Colchicine."
The funny this is I control my gout naturally now without drugs and use some of what is recommended to do with Probenecid, which upset my stomach terribly.
Drink 10 or more full glasses of water a day while taking probenecid. This will help to prevent formation of kidney stones and other possible kidney problems by removing excess uric acid. Probenecid works best when the urine is alkaline (non-acidic). Ask your prescriber or health care professional about which foods or juices to avoid, and about other foods, beverages or antacids that may help to make the urine alkaline.